Barshop Investigator Awarded $2.7 Million R01 for mTOR Inhibition Study
Adam Salmon, PhD, an Assistant Professor of Research in the Department of Molecular Medicine and the Barshop Institute, has received a $2.7 million R01 award from the NIH National Institute on Aging to study the role of mTOR inhibition in longevity and aging in a non-human primate. During this five-year study, Dr. Salmon’s lab will test whether mTOR inhibition through chronic administration of rapamycin delays aging in a non-human primate, the common marmoset, as an important step towards translational approaches to delay age-related disease in humans. While inhibition of the mTOR signaling pathway has been shown to extend both lifespan and healthspan in mice, the implications of these findings for improving normal, healthy aging in humans is largely unknown. Dr. Salmon’s study is a promising step towards bridging this knowledge gap.