Publications

APOE2 orchestrated differences in transcriptomic and lipidomic profiles of postmortem AD brain. Lefterov I, Wolfe CM, Fitz NF, Nam KN, Letronne F, Biedrzycki RJ, Kofler J, Han X, Wang J, Schug J, Koldamova R Alzheimers Res Ther. 2019 Dec 30;11(1):113. doi: 10.1186/s13195-019-0558-0. Abstract: BACKGROUND: The application of advanced sequencing technologies and improved mass-spectrometry platforms revealed […]

Nexrutine and exercise similarly prevent high grade prostate tumors in transgenic mouse model. Patel DI, Abuchowski K, Bedolla R, Rivas P, Musi N, Reddick R, Kumar AP PLoS One. 2019 Dec 19;14(12):e0226187. doi: 10.1371/journal.pone.0226187. eCollection 2019. Abstract: The purpose of this investigation was to compare the antitumorigenic effects of the natural product Nexrutine to voluntary […]

Aging Induces an Nlrp3 Inflammasome-Dependent Expansion of Adipose B Cells That Impairs Metabolic Homeostasis. Camell CD, Günther P, Lee A, Goldberg EL, Spadaro O, Youm YH, Bartke A, Hubbard GB, Ikeno Y, Ruddle NH, Schultze J, Dixit VD Cell Metab. 2019 Dec 3;30(6):1024-1039.e6. doi: 10.1016/j.cmet.2019.10.006. Epub 2019 Nov 14. Abstract: During aging, visceral adiposity is […]