mTOR drives cerebrovascular, synaptic, and cognitive dysfunction in normative aging. Van Skike CE, Lin AL, Roberts Burbank R, Halloran JJ, Hernandez SF, Cuvillier J, Soto VY, Hussong SA, Jahrling JB, Javors MA, Hart MJ, Fischer KE, Austad SN, Galvan V. Aging Cell. 2020 Jan;19(1):e13057. doi: 10.1111/acel.13057. Epub 2019 Nov 6. Abstract: Cerebrovascular dysfunction and cognitive […]
read moreAge-dependent autophagy induction after injury promotes axon regeneration by limiting NOTCH. Ko SH, Apple EC, Liu Z, Chen L Autophagy. 2020 Jan 13:1-17. doi: 10.1080/15548627.2020.1713645. [Epub ahead of print] Abstract: Macroautophagy/autophagy is essential for maintaining cellular homeostasis through the degradation of organelles and proteins. It also has a prominent role in modulating aging. However, the […]
read moreAcarbose improved survival for Apc+/Min mice. Dodds SG, Parihar M, Javors M, Nie J, Musi N, Dave Sharp Z, Hasty P Aging Cell. 2020 Jan 6:e13088. doi: 10.1111/acel.13088. [Epub ahead of print] Abstract: Acarbose blocks the digestion of complex carbohydrates, and the NIA Intervention Testing Program (ITP) found that it improved survival when fed to […]
read moreTORwards a Victory Over Aging. Lamming DW, Salmon AB J Gerontol A Biol Sci Med Sci. 2020 Jan 1;75(1):1-3. doi: 10.1093/gerona/glz212.
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