Hydrogen sulfide ameliorates aging-associated changes in the kidney.

May 1, 2018

Lee HJ, Feliers D, Barnes JL, Oh S, Choudhury GG2, Diaz V, Galvan V, Strong R, Nelson J, Salmon A, Kevil CG, Kasinath BS Geroscience. 2018 Apr;40(2):163-176. doi: 10.1007/s11357-018-0018-y. Epub 2018 May 1. PMCID: PMC5964063 Abstract Aging is associated with replacement of normal kidney parenchyma by fibrosis. Because hydrogen sulfide (H2S) ameliorates kidney fibrosis in […]

Metabolic consequences of long-term rapamycin exposure on common marmoset monkeys (Callithrix jacchus).

November 1, 2015

Ross C, Salmon A, Strong R, Fernandez E, Javors M, Richardson A, Tardif S Aging (Albany NY). 2015 Nov;7(11):964-73. doi: 10.18632/aging.100843 Abstract Rapamycin has been shown to extend lifespan in rodent models, but the effects on metabolic health and function have been widely debated in both clinical and translational trials. Prior to rapamycin being used [...]

Testing Efficacy of Administration of the Antiaging Drug Rapamycin in a Nonhuman Primate, the Common Marmoset

May 1, 2015

Tardif S, Ross C, Bergman P, Fernandez E, Javors M, Salmon A, Spross J, Strong R, Richardson A J Gerontol A Biol Sci Med Sci. 2015 May;70(5):577-87. doi: 10.1093/gerona/glu101. Epub 2014 Jul 19. Abstract This report is the first description of dosing procedures, pharmacokinetics, biochemical action, and general tolerability of the antiaging drug rapamycin in [...]