San Antonio Claude D. Pepper Center
October 13, 2018
J Gerontol A Biol Sci Med Sci. 2018 Oct 13. doi: 10.1093/gerona/gly237. [Epub ahead of print] DOI: 10.1093/gerona/gly237 Abstract We evaluated whether the marmoset, a nonhuman primate, can serve as a good model to study aging related changes in the kidney by employing healthy young and aged marmosets of both sexes. Aging was associated with […]
October 12, 2018
Sills AM, Artavia JM, DeRosa BD, Ross CN, Salmon AB American Journal of Primatology. 2018 Oct 12:e22927. doi: 10.1002/ajp.22927. [Epub ahead of print]. Abstract: Interventions to extend lifespan and improve health with increasing age would have significant impact on a growing aged population. There are now several pharmaceutical interventions that extend lifespan in laboratory rodent [...]October 11, 2018
Musi N, Valentine JM, Sickora KR, Baeuerle E, Thompson CS, Shen Q, Orr ME Aging Cell. 2018 Dec;17(6):e12840. doi: 10.1111/acel.12840. Epub 2018 Oct 11. Abstract: Tau protein accumulation is the most common pathology among degenerative brain diseases, including Alzheimer’s disease (AD), progressive supranuclear palsy (PSP), traumatic brain injury (TBI), and over twenty others. Tau-containing neurofibrillary […]
May 1, 2018
Lee HJ, Feliers D, Barnes JL, Oh S, Choudhury GG2, Diaz V, Galvan V, Strong R, Nelson J, Salmon A, Kevil CG, Kasinath BS Geroscience. 2018 Apr;40(2):163-176. doi: 10.1007/s11357-018-0018-y. Epub 2018 May 1. PMCID: PMC5964063 Abstract Aging is associated with replacement of normal kidney parenchyma by fibrosis. Because hydrogen sulfide (H2S) ameliorates kidney fibrosis in […]
February 3, 2018
Kraig E, Linehan LA, Liang H, Romo TQ, Liu Q, Wu Y, Benavides AD, Curiel TJ, Javors MA, Musi N, Chiodo L, Koek W, Gelfond JAL, Kellogg DL Jr Exp Gerontol. 2018 May;105:53-69. doi: 10.1016/j.exger.2017.12.026. Epub 2018 Feb 3. Abstract: Inhibition of the mechanistic target of rapamycin (mTOR) pathway by rapamycin (RAPA), an FDA-approved immunosuppressive […]
December 7, 2017
Ross CN, Austad S, Brasky K, Brown CJ, Forney LJ, Gelfond JA, Lanford R, Richardson A, Tardif SD Aging (Albany NY). 2017 Dec 7;9(12):2544-2558. doi: 10.18632/aging.101340. Abstract: A specific pathogen free (SPF) barrier colony of breeding marmosets (Callithrix jacchus) was established at the Barshop Institute for Longevity and Aging Studies. Rodent and other animal models […]
October 9, 2017
Reveles KR, Ryan CN, Chan L, Cosimi RA, Haynes WL Gut. 2018 Jul;67(7):1369-1370. doi: 10.1136/gutjnl-2017-315306. Epub 2017 Oct 9. Excerpt: We read with great interest the recent publications in Gut by Imhann et al and Jackson et al, which assessed the impact of proton pump inhibitor (PPI) use on gut microbiota diversity and composition in […]
September 5, 2017
Bandeen-Roche K, Espinoza SE J Am Geriatr Soc. 2017 Nov;65(11):2455-2456. doi: 10.1111/jgs.15034. Epub 2017 Sep 5. Excerpt We congratulate Lauren Pollack, Thuy-Tien Dam, and their colleagues on their intriguing study of frailty status transitions in older men.1 By describing the natural history of frailty progression—and remission, the authors’ study lays epidemiological groundwork for evaluating public […]
January 28, 2017
Wang CP, Lorenzo C, Habib SL, Jo B, Espinoza SE J Diabetes Complications. 2017 Apr;31(4):679-686. doi: 10.1016/j.jdiacomp.2017.01.013. Epub 2017 Jan 28. Abstract: AIMS: To identify distinct temporal likelihoods of age-related comorbidity (ARC) diagnoses: cardiovascular diseases (CVD), cancer, depression, dementia, and frailty-related diseases (FRD) in older men with type 2 diabetes (T2D) but ARC naïve initially, […]
July 22, 2016
Moving toward ‘common’ use of the marmoset as a non-human primate aging model Adam B. Salmon Pathobiol Aging Age Relat Dis. 2016; 6: 10.3402/pba.v6.32758. Published online 2016 Jul 22. doi: 10.3402/pba.v6.32758 Abstract Great leaps forward in our understanding of the basic biology of aging, including interventions that extend longevity, have come about from using common [...]